SNC80: A potent, selective,non-peptide δ opioid receptor agonist

SNC80 is a powerful tool with which to explore the role
of δ opioid receptors in the central nervous system (CNS).
δ Opioid receptors are widely distributed throughout the
brain, spinal cord and peripheral sensory systems1 and are
important in many CNS regulatory functions such as antinociception,
2 regulation of stress adaptation 3 and modulation
of immune responses.4 SNC80 is a potent δ opioid
receptor agonist both in vitro and in vivo.1,5,6,7

For more information regarding opioid receptor agonists
and antagonists, please refer to The RBI Handbook
of Receptor Classification and Signal Transduction (Product
Code S 8188).

References
1. Quock, R.M. et al., Pharmacol Rev., 51, 503-532 (1999).
2. Terenius, L., Ups. J. Med. Sci., 105, 1-15 (2000).
3. Drolet, G. et al., Prog. Neuropsychopharmacol. Biol. Psychiatry, 25,
729-741 (2001).
4. McCarthy, L. et al., Drug Alcohol Depend., 62, 111-123 (2001).
5. Calderon, S.N. et al., J. Med. Chem., 37, 2125-2128 (1994).
6. Calderon, S.N. et al., J Med. Chem., 40, 695-704 (1997).
7. Bilsky, E.J. et al., J. Pharmacol. Exp. Ther., 273, 359-366 (1995).

ORDERING INFORMATION (only labs who have the required licence)

Product                  Name/Code                   Unit Price
SNC80                           5 mg                       285 Euro
S 2812                         25 mg                       1000 Euro