DESCRIPTION
Calcium is measured to monitor diseases of the bone or calcium regulation
disorders. Increased calcium levels in serum are reported in
hyperparathyroidism, metastatic bone lesions and hypervitaminosis, while
decreased levels are observed in hypoparathyroidism, nephrosis, rickets,
steatorrhea, nephritis and calcium-losing syndromes. Urinary calcium levels
aid the clinician in understanding how the kidneys handle calcium in certain
diseases of the parathyroid gland. Urinary calcium levels are also essential
in the medical evaluation of kidney stones.
Simple, direct and automation-ready procedures for measuring calcium
concentration in biological samples are very popular in clinical studies.
BioAssay Systems' calcium assay kit is designed to measure calcium directly
in biological samples without any pretreatment. A phenolsulphonephthalein
dye in the kit forms a very stable blue colored complex specifically with
free calcium. The intensity of the color, measured at 612 nm, is directly
proportional to the calcium concentration in the sample. The optimized
formulation minimizes any interference by substances such as magnesium,
lipid, protein and bilirubin.
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