DESCRIPTION
Albumin is the most abundant plasma protein in humans. It accounts for about
60% of the total serum protein. Albumin plays important physiological roles,
including maintenance of colloid osmotic pressure, binding of key substances
such as long-chain fatty acids, bile acids, bilirubin, haematin, calcium,
magnesium. It has anti-oxidant and anticoagulant effects, and also acts as a
carrier for nutritional factors and drugs, as an effective plasma pH buffer.
Serum albumin is a reliable prognostic indicator for morbidity and
mortality, liver disease, nephritic syndrome, malnutrition and
protein-losing enteropathies. High levels are associated with dehydration.
Simple, direct and automation-ready procedures for measuring albumin
concentration in biological samples are very popular in clinical studies.
BioAssay Systems' BCP albumin assay kit is designed to measure albumin
directly in biological samples without any pretreatment. The improved method
utilizes bromcresol purple that forms a colored complex specifically with
albumin. The intensity of the color, measured at 620nm, is directly
proportional to the albumin concentration in the sample. The optimized
formulation substantially reduces interference by substances in the raw
samples.
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