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Anti-Jnk Inhibitor Protein 1 (JIP1) Monoclonal Reactivity: Human References: Yasuda et al. (1999) The JIP group of mitogen-activated protein kinase scaffold proteins. Mol Cell Biol. 19:7245-54. Whitmarsh et al. (2001) Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev. 15:2421-32. Kelkar et al. (2003) Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). Proc Natl Acad Sci U S A. 19;100(17):9843-8. Inventor: Roger Davis, Ph.D. Docket: UMMC 06-52
Anti-Jnk Inhibitor Protein 2 (JIP2) Monoclonal Reactivity: Human References: Yasuda et al. (1999) The JIP group of mitogen-activated protein kinase scaffold proteins. Mol Cell Biol. 19:7245-54. Whitmarsh et al. (2001) Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev. 15:2421-32. Kelkar et al. (2003) Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). Proc Natl Acad Sci U S A. 19;100(17):9843-8. Inventor: Roger Davis, Ph.D. Docket: UMMC 06-53
Anti-Zinc finger protein (ZPR1) Monoclonal Reactivity: human, mouse References: Gangwani et al. (2001) Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein. Nature Cell Bio 3: 376-383. Gangwani et al. (2005) ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to cajal bodies. Mol and Cell Bio 25: 2744-2756. Inventor: Roger Davis, Ph.D.
Anti-Toll-like receptor 2 (TLR2) Monoclonal Reactivity: human Reference: Sandor et al. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFқB signaling. Journal of Cell Biology 162: 1099-1110. Inventor: Evelyn Kurt-Jones
Anti-Norwalk Virus (1C9 and 1D8) Monoclonal References: Herrmann et al. (1995) Monoclonal antibodies for detection of Norwalk virus antigen in stools. J Clin Microbio 33:2511-2513. Additional Information: Antibodies against 8FIIa strain of Norwalk Virus, no cross reactivity with other caliciviruses, 1D8 antibody reacts to the N terminus of the viral capsid. Inventor: John Hermann, Ph.D. Docket: UMMC 95-22
Anti-Astrovirus (8E7) Monoclonal Inventor: John Hermann, Ph.D. References: Herrmann et al. (1990) Diagnosis of astrovirus gastroenteritis by antigen detection with monoclonal antibodies. J Infect Dis 2:226-9. Additional Information: Reacts with all known types of astroviruses which cause gastroenteritis, no cross reactivity with other caliciviruses, antibody isotype IgG1 Docket: UMMC 89-02
Rotavirus (3F7) Monoclonal Reference: Cukor et al. (1984) Detection of Rotavirus in human stools by using monoclonal antibody. Journal of Clinical Microbiology 888-893. Additional Information: ATTC# SD4052, no cross reactivity with other caliciviruses. Docket: UMMC 84-02. Inventor: John Hermann, Ph.D.
Anti-Newcastle disease virus hemagglutinin neuraminidase (HN4a) Monoclonal References: Iorio et al. (1983) Monoclonal antibodies to Newcastle disease virus: delineation of four epitopes on the HN glycoprotein. J Virology 48: 440-450. Iorio et al. (1984) Neutralization of Newcastle disease virus by monoclonal antibodies to the hemagglutinin-neuraminidase glycoprotein: requirement for antibodies to four sites for complete neutralization. J Virology 51:445-451. Additional information: Australia-Victoria virus strain Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology Docket: UMMC 02-21
Anti-Newcastle disease virus hemagglutinin neuraminidase (HN14f) Monoclonal Reference: Available upon request Additional information: Australia-Victoria virus strain, antibody recognizes a linear epitope in the protein Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology Docket: UMMC 01-38
Anti-Newcastle disease virus fusion protein (IC114) Monoclonal Reference: Available upon request Additional information: Australia-Victoria virus strain Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology Docket: UMMC 01-35
Anti-Ubiquitin Activating E1 Enzyme Monoclonal Reference: Available upon request Inventor: Kenneth Rock, MD, Chair of Pathology Docket: UMMC00-32
Polyclonal Antibodies:
Anti-mitofilin (specific to mitochondria) Rabbit polyclonal Reactivity: Human, mouse, rat, cat, dog Reference: Odgren et al. (1996) Molecular characterization of mitofilin (HMP), a mitochondria-associated protein with predicted coiled coil and intermembrane space targeting domains. J Cell Science 109:2253-2264. Additional information: This antibody detects all known mitofilin isoforms in western blots and intensely labels mitochondria in immunofluorescense and immuno-electron microscopy. Docket: UMMC05-63
Anti-tub 1 (regulator of fat storage and life span) Rabbit polyclonal Reactivity: C. elegans Reference: Mukhopadhyay et al. (2005) C. elegans tubby regulates life span and fat storage by two independent mechanisms. Cell Metabolism 2:35-42. Inventor: Heidi Tissenbaum Ph.D. Docket: UMMC05-11
Anti-SIR2.1 (silent information regulator 2, family of NAD+-dependent protein deacetylases) Rabbit polyclonal Reactivity: C. elegans Additional Information: Polyclonal antibodies available for both the full-length and N' truncated his tagged SIR2.1 Inventor: Heidi Tissenbaum Ph.D. Docket: UMMC05-10
Anti-DAF-16 (forkhead transcription factor) Rabbit polyclonal Reactivity: C. elegans Reference: Wook Oh et al. (2005) Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nature Genetics Inventor: Heidi Tissenbaum Ph.D. Docket: UMMC05-09
Anti-DAF-3(forkhead transcription factor) Rabbit polyclonal Reactivity: C. elegans Reference: manuscript accepted in Cell Inventor: Marian Walhout, Ph.D., Program Gene Function & Expression Docket: UMMC05-09
Anti-JNK-1 (c-Jun N-terminal kinase) Rabbit polyclonal Reactivity: C. elegans Reference: Wook Oh et al. (2005) JNK regulates lifespan in C. elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. PNAS 102: 4494-4499. Inventor: Heidi Tissenbaum Ph.D. Docket: UMMC05-08
Anti-HMGN1 (high mobility group protein 14) Rabbit polyclonal Reactivity: Human Reference: Hill et al. (2005) Effects of HMGN1 on chromatin structure and SWI/SNF-mediated chromatin remodeling. J of Biological Chemistry 280: 41777-41783. Docket: UMMC05-03
Anti-DNA-binding protein B (dbpB) Rabbit polyclonal Reactivity: Human Reference: Leonard et al. (1998) Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. J of Biological Chemistry 273: 5443-5446. Additional information: Antibody against C-terminal 15 amino acids or entire His-tagged dbpB protein Inventor: Jack Leonard, Ph.D.
Anti-Selenodeiodinase type I (SeD1) Rabbit polyclonal Reactivity: rat Reference: Leonard et al. (1999) The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat. Endocrinology 140: 2206-2215. Additional information: Antibody against C-terminus Inventor: Jack Leonard, Ph.D.
Anti-p27 (27 kDa substrate binding subunit of type I deiodinase) Rabbit polyclonal Reactivity: rat References: Leonard et al. (2001) Characterization of the subunit structure of the catalytically active type I iodothyronine. J of Biological Chemistry 276: 2600-2607. Leonard et al. (2005) Characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases. J of Biological Chemistry 280: 11093-1110. Additional information: Antibody against 21 C-terminal amino acids Inventor: Jack Leonard, Ph.D.
Anti-Selenodeiodinase type II (SeD2) Rabbit polyclonal Reactivity: rat References: Leonard et al. (1999) The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat. Endocrinology 140: 2206-2215. Leonard et al. (2003) Hypothalamic type II iodothyronine deiodinase: a light and electronmicroscopic study. Brain Research 976: 130-134. Leonard et al. (2005) Characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases. J of Biological Chemistry 280: 11093-1110. Additional information: Antibody against C-terminus or catalytic core of SeD2 Inventor: Jack Leonard, Ph.D.
Anti-p29 (29 kDa substrate binding subunit of type II deiodinase) Rabbit polyclonal Reactivity: rat Reference: Leonard et al. (2000) Cloning, expression, and functional characterization of the substrate binding subunit of type II iodothyronine 5’-deiodinase. J of Biological Chemistry 275: 25194-25201. Additional information: Antibody against C-terminus Inventor: Jack Leonard, Ph.D.
Anti-Selenodeiodinase type III (SeD3) Rabbit polyclonal Reactivity: chicken Reference: Leonard et al. (2002) Specific detection of type III iodothyronine deiodinase protein in chicken cerebellar purkinje cells. Endocrinology 143: 2700-2707. Inventor: Jack Leonard, Ph.D.
Anti-Myosin Va Rabbit polyclonal Reactivity: rat Reference: Leonard et al. (2000) Myosin V plays an essential role in the thyroid hormone-dependent endocytosis of type II iodothyronine 5’-deiodinase. J of Biological Chemistry 275: 31701-31707. Leonard et al. (2001) Real-time visualization of processive myosin 5a-mediated vesicle movement in living astrocytes. J of Biological Chemistry 276: 35652-35659 Additional information: Antibody against C-terminus or coiled-coiled domain Inventor: Jack Leonard, Ph.D. Docket: UMMC 05-44
Anti-Protein Disulfide Isomerase (PDI) Rabbit polyclonal Reactivity: rat Reference: Leonard et al. (1991) Characterization of a n-bromoacetyl-l-thyroxine affinity- labeled 55-kD protein as protein disulfide isomerase in cultured glial cells. Endocrinology 129: 2011-2016. Inventor: Jack Leonard, Ph.D., Professor Physiology Anti-α-nucleolin Rabbit polyclonal Reactivity: rat Inventor: Jack Leonard, Ph.D.
Anti-EBP-50 (ezrin-binding phosphoprotein) Rabbit polyclonal Reactivity: human, rat, mouse Reference: Lambert et al. (2003) Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of ranvier. J of Cell Biology 162: 489-498. Inventor: Stephen Lambert, Ph.D. Docket: UMMC 03-28
Anti-supervillin/archvillin Rabbit polyclonal Reactivity: human, mouse, bovine, hamster References: Luna et al. (2002) Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes. J of Bio Chem 277: 43399-43409. Luna et al. (2003) Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton. J Cell Science 116: 2261-2275. Luna et al. (2004) Smooth muscle archvillin: a novel regulator of signaling and contractility in vascular smooth muscle. J Cell Science 117:5043-5057. Additional information: amino acids 1-340, hybridomas available upon request Inventor: Beth Luna, Ph.D. Docket: UMMC 03-37
Anti-pepA (SVIL) Rabbit polyclonal Reactivity: bovine Reference: Luna et al. (2003) Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton. J of Cell Science 116: 2261-2275. Additional information: amino acids 900-918 Inventor: Beth Luna, Ph.D.
Anti-phospho-specific IRE1α Rabbit polyclonal Reactivity: human, rat, mouse Reference: Available upon request Inventor: Fumihiko Urano, MD, Ph.D. Docket: UMMC 05-18
Anti-total -specific IRE1α Rabbit polyclonal Reactivity: human, rat, mouse Reference: Available upon request Inventor: Fumihiko Urano, MD, Ph.D. Docket: UMMC 06-56
Anti-WFS1 (Wolfram syndrome 1 gene product) Rabbit polyclonal Reactivity: human, rat Reference: Takeda et al. (2001) WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Human Molecular Genetics 10: 477-484. Additional information: Antibody against C-terminus Inventor: Fumihiko Urano, MD, Ph.D. Docket: UMMC 06-54 |
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