Anti-supervillin/archvillin

Monoclonal

Inventor: Beth Luna, Ph.D.

 

Anti-Astrovirus (8E7)

Monoclonal

Inventor: John Hermann, Ph.D.

References:  

Herrmann et al. (1990) Diagnosis of astrovirus gastroenteritis by antigen detection with monoclonal antibodies. J Infect Dis 2:226-9. 

Additional Information: Reacts with all known types of astroviruses which cause gastroenteritis, no cross reactivity with other caliciviruses, antibody isotype IgG1

Docket: UMMC 89-02

 

Rotavirus (3F7)

Monoclonal

Reference:

Cukor et al. (1984) Detection of Rotavirus in human stools by using monoclonal antibody. Journal of Clinical Microbiology  888-893.

Additional Information: ATTC# SD4052, no cross reactivity with other caliciviruses.

Docket: UMMC 84-02.

Inventor: John Hermann, Ph.D.

 

Anti-Newcastle disease virus hemagglutinin neuraminidase (HN4a)

Monoclonal

References:

Iorio et al. (1983) Monoclonal antibodies to Newcastle disease virus: delineation of four epitopes on the HN glycoprotein. J Virology  48: 440-450.

Iorio et al. (1984) Neutralization of Newcastle disease virus by monoclonal antibodies to the hemagglutinin-neuraminidase glycoprotein: requirement for antibodies to four sites for complete neutralization. J Virology 51:445-451.

Additional information:  Australia-Victoria virus strain

Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology

Docket: UMMC 02-21

 

Anti-Newcastle disease virus hemagglutinin neuraminidase (HN14f)

Monoclonal

Reference: Available upon request

Additional information: Australia-Victoria virus strain, antibody recognizes a linear epitope in the protein

Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology

Docket: UMMC 01-38

 

Anti-Newcastle disease virus fusion protein (IC114)

Monoclonal

Reference: Available upon request

Additional information:  Australia-Victoria virus strain

Inventor: Ronald Iorio, Ph.D., Professor Molecular Genetics & Microbiology

Docket: UMMC 01-35

 

 

Polyclonal Antibodies:

 

Anti-tub 1 (regulator of fat storage and life span)

Rabbit polyclonal

Reactivity: C. elegans

Reference: Mukhopadhyay et al. (2005) C. elegans tubby regulates life span and fat storage by two independent mechanisms. Cell Metabolism 2:35-42.

Inventor: Heidi Tissenbaum Ph.D.

Docket: UMMC05-11

 

Anti-SIR2.1 (silent information regulator 2, family of NAD+-dependent protein deacetylases)

Rabbit polyclonal

Reactivity: C. elegans

Additional Information: Polyclonal antibodies available for both the full-length and N' truncated his tagged SIR2.1

Inventor: Heidi Tissenbaum Ph.D.

Docket: UMMC05-10

 

 

Anti-DAF-3 (forkhead transcription factor)

Rabbit polyclonal

Reactivity: C. elegans

Reference: manuscript accepted in Cell

Inventor: Marian Walhout, Ph.D., Program Gene Function & Expression

Docket: UMMC05-09

 

Anti-DNA-binding protein B (dbpB)

Rabbit polyclonal

Reactivity: Human

Reference: Leonard et al. (1998) Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. J of Biological Chemistry 273: 5443-5446.

Additional information: Antibody against C-terminal 15 amino acids or entire His-tagged dbpB protein

Inventor: Jack Leonard, Ph.D.

 

Anti-Selenodeiodinase type I (SeD1)

Rabbit polyclonal

Reactivity: rat

Reference: Leonard et al. (1999) The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat. Endocrinology  140: 2206-2215.

Additional information: Antibody against C-terminus

Inventor: Jack Leonard, Ph.D.

 

Anti-p27 (27 kDa substrate binding subunit of type I deiodinase)

Rabbit polyclonal

Reactivity: rat

References:

Leonard et al. (2001) Characterization of the subunit structure of the catalytically active type I iodothyronine. J of Biological Chemistry 276: 2600-2607.

Leonard et al. (2005) Characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases. J of Biological Chemistry 280: 11093-1110.

Additional information: Antibody against 21 C-terminal amino acids 

Inventor: Jack Leonard, Ph.D.

 

Anti-Selenodeiodinase type II (SeD2)

Rabbit polyclonal

Reactivity: rat

References:

Leonard et al. (1999) The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat. Endocrinology  140: 2206-2215.

Leonard et al. (2003) Hypothalamic type II iodothyronine deiodinase: a light and electronmicroscopic study. Brain Research 976: 130-134.

Leonard et al. (2005) Characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases. J of Biological Chemistry 280: 11093-1110.

Additional information: Antibody against C-terminus or catalytic core of SeD2

Inventor: Jack Leonard, Ph.D.

 

Anti-p29 (29 kDa substrate binding subunit of type II deiodinase)

Rabbit polyclonal

Reactivity: rat

Reference: Leonard et al. (2000) Cloning, expression, and functional characterization of the substrate binding subunit of type II iodothyronine 5’-deiodinase. J of Biological Chemistry 275: 25194-25201.

Additional information: Antibody against C-terminus

Inventor: Jack Leonard, Ph.D.

 

Anti-Selenodeiodinase type III (SeD3)

Rabbit polyclonal

Reactivity: chicken

Reference: Leonard et al. (2002) Specific detection of type III iodothyronine deiodinase protein in chicken cerebellar purkinje cells. Endocrinology  143: 2700-2707.

Inventor: Jack Leonard, Ph.D.

 

Anti-Myosin Va

Rabbit polyclonal

Reactivity: rat

Reference:

Leonard et al. (2000) Myosin V plays an essential role in the thyroid hormone-dependent endocytosis of type II iodothyronine 5’-deiodinase. J of Biological Chemistry  275: 31701-31707.

                Leonard et al. (2001) Real-time visualization of processive myosin 5a-mediated vesicle movement in living astrocytes. J of Biological Chemistry 276: 35652-35659

Additional information: Antibody against C-terminus or coiled-coiled domain

Inventor: Jack Leonard, Ph.D.

Docket: UMMC 05-44

 

Anti-Protein Disulfide Isomerase (PDI)

Rabbit polyclonal

Reactivity: rat

Reference: Leonard et al. (1991) Characterization of a n-bromoacetyl-l-thyroxine affinity- labeled 55-kD protein as protein disulfide isomerase in cultured glial cells. Endocrinology 129: 2011-2016.

Inventor: Jack Leonard, Ph.D., Professor Physiology

 

Anti-α-nucleolin

Rabbit polyclonal

Reactivity: rat

Inventor: Jack Leonard, Ph.D.

 

Anti-EBP-50 (ezrin-binding phosphoprotein)

Rabbit polyclonal

Reactivity: human, rat, mouse

Reference: Lambert et al. (2003) Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of ranvier. J of Cell Biology 162: 489-498.

Inventor: Stephen Lambert, Ph.D.

Docket: UMMC 03-28

 

Anti-pepA (SVIL)

Rabbit polyclonal

Reactivity: bovine

Reference: Luna et al. (2003) Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton. J of Cell Science 116: 2261-2275.

Additional information: amino acids 900-918

Inventor: Beth Luna, Ph.D.

 

 

Anti-WFS1 (Wolfram syndrome 1 gene product)

Rabbit polyclonal

Reactivity: human, rat

Reference: Takeda et al. (2001) WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Human Molecular Genetics  10: 477-484.

Additional information: Antibody against C-terminus

Inventor: Fumihiko Urano, MD, Ph.D.

Docket: UMMC 06-54