HTGF - beta-2 recombinant
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Product Details: Human transforming growth factor beta-2 (TGF - beta-2) recombinant

Basic Information

 
Product ID: GF-240-2
Product Name: Human transforming growth factor beta-2 (TGF - beta-2) recombinant
Unit: 5µg
Price: 315 Euro
Availability: Available
Category: Growth Factors, Cytokines, Receptors and their Antibodies
Subcategory: Growth Factors/Cytokines/Enzymes

 

Product Details

 
Description: Human Transforming Growth Factor beta2 (TGF- beta2) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF- beta2 is a disulfide-linked homodimer of two chains composed of 112 amino acid residues each. There is a 70% homology between human TGF- beta2 and human TGF- beta1.

Human TGF- beta2 is produced in genetically engineered e. coli bacteria, and purified by sequential chromatography.

 
Molecular Weight: 25 KDa (dimeric protein)
Biological Activity: The biological activity of human TGF-&# beta2 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.

 
Formulation: 1 mg/ml (pH 2.5). CAUTION: Since the volume supplied is small, we advise our customers to dilute this material to a working stock solution. To remove partial aliquots in not recommended.
Purity: Over 98% pure by non-reduced SDS gel electrophoresis.
Storage Conditions: Store at -80°C.
Stability: Several months at -80°C.
Temperature: -80°C
References: 1. Moustakas, A., Lin, H.Y., Henis, Y.I., Plamondon, J., O'Conner-McCourt, M.D., and Lodish, H.F., (1993) The Journal of Biological Chemistry, Vol 268, 30, October, 22215-22218.
2. Geiser, A.G., Burmester, J.K., Webbink, R., Roberts, A.B., and Sporn, M.B., (1992). The Journal of Biological Chemistry, Vol 267, 4, February, 2588-2593.