Glucose Transporter (Gluts1-13) Antibodies

   

M= Mouse; R=Rat; H=Human; Rb=Rabbit; G=goat; B=Bovine, MO=Monkey; P=pig; CT= near C-terminus; NT=near N-terminus; Internal=Middle of protein. EC=extracellular; CP=cytoplasmic domains *


Glucose Transporter (Gluts1-13) Antibodies-General Information

Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (Glut or SLC2A family). Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 9 proteins (Glut-1 to Glut-14, Mol. Wt. 40-60 kDa). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic. There is a large extracellualr domain between TM1-TM2 and a cytoplasmic domain between TM6-TM7. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting.

Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-1 mediates glucose transport into red cells, and throughout the blood brain barrier. It is ubiquitously expressed and transport glucose in most cells. Glut-2 provides glucose to the liver and pancreatic cells. Glut-3 is the main transporter in neurons, whereas Glut-4 is primarily expressed in muscle and adipose tissue and regulated by insulin. Glut-5 transports fructose in intestine and testis. Glut-6 name was previously assigned to a pseudoegene. Now Glut-9 has been renamed as Glut-6 (human 507 aa; ~45% identity with Glut-8). It is highly expressed in brain, spleen, and leukocytes. Glut-7, expressed in liver and other gluconeogenic tissues, mediates glucose flux across endoplasmic reticulum membrane. Most recently, Glut-8 (mouse/rat/human 477 aa, ~30% identity with Glut-1) has been cloned and characterized. High levels are found in adult testis and placenta. Human Glut-9 (540 aa; chromosome 4p15.3-p16) is approx 45% identical with Glut-5, and 38% with Glut-1. It is expressed in kidney, followed by liver. Glut-9 is also detected in placenta, lung, blood leukocytes, heart, and skeletal muscle. Human Glut-10 (541 aa, chromosome 20q13.1; ~30-35% homology with Glut-3 and Glut-8) has been identified as a candidate gene for NIDDM susceptibility. It is widely expressed with highest levels in liver and pancreas. Glut-11 (496 aa, chromosome 22q11.2; ~41% identity with Glut-5) is expressed in heart and skeletal muscle. Recently, a few novel members of Glut family have been identified. Glut-12 (human 617 aa; 29% identity with Glut-4 and 40% with Glut-10). It is expressed in skeletal muscle, adipose tissue, and small intestine. Glut-13 or H+ myo-inositol transporter (HMIT, rat 618 aa; human 629 aa; ~36% identity with Glut-8). It is predominantly expressed in brain.

ADI has produced highly specific rabbit-anti Glut-1-13 using antigenic sequences unique to each protein. These antibodies do not crossreact with each other and can be used to study specific Gluts in mouse, rat, and human tissues. Availability of multiple antibodies to the same protein should help select antibodies with more interspecies crossreactivity, and to achieve better results in a given technique. The control/blocking peptides, used for immunization, are also available to determine specificity of antibodies.

Information on Antibodies to Sodium Glucose Transproters (SGLT1-4)

New Nomenclature (HUGO) of Gluts

 

For A review of the nomenclature and details see Joost, H-G et al (2002) Am. J. Endo. Metabol. 282, E974-E976

References:
Glut-1: Mueckler M et al (1985) Science 229, 941-985; Fukumoto,H et al (1989) Diabetes 37, 657-661 Glut-2: Fukumoto H et al (1989) JBC 264, 7776-7779
Glut-3: Kayano T et al (1988) JBC 263, 15245-15248
Glut-4: Fukumoto H et al (1989) JBC 264, 7776-7779; Buse JB et al (1992) Diabetes 41, 1436-1445; Chiaramonte,R. et al (1993) Gene 130, 307-308; Choi WH et al (1991) Diabetes 40, 1712
Glut-5: Kayano T et al (1990) JBC 265, 13276-13282
Glut-6: Doege H et al (2000) Biochem. J. 350, 771-776
Glut-7: Waddell ID et al (1992) Biochem. J. 286, 173-177
Glut-8: Carayannopoulos MO et al (2000) PNAS 13, 7313-7318; Doege H et al (2000) JBC 275, 16275-16280; Ibberson M et al (2000) JBC 275, 4607-4612
Glut-9: Phay JE et al (2000) Genomics 66, 217-220
Glut-10: McVie-Wylie AJ et al (2001) Genomics 72, 113-117
Glut-11: Doege H et al (2001) Biochem J. 359, 443-459
Glut-12: Rogers S et al (2002) Am. J. Endocrinol. Metabol. 282, E733-E738
Glut-13: Uldry M et al (2001) EMBO J. 20, 4467-4477

List of publications using ADI's Antibodies to various Glucose transporters

glut1 Bindra RJ (2002), VHL-mediated Hypoxia Regulation of Cyclin D1 in Renal Carcinoma Cells Cancer Res. 62: 3014 - 3019 , WB, , nonrl and hyp cancer cells

glut1 Tong, Haiyan (2000), Preconditioning Enhanced Glucose Uptake Is Mediated by p38 MAP Kinase Not by Phosphatidylinositol 3-Kinase J. Biol. Chem. 2000 275: 11981-11986, w , rat heart

glut1 Cockman, M E (2000), Hypoxia Inducible Factor- Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein J. Biol. Chem. 2000 275: 25733-25741 , WB, , IP,

glut1 Greenberg CC (2003), Protein Targeting to Glycogen Overexpression Results in the Specific Enhancement of Glycogen Storage in 3T3-L1 Adipocytes J. Biol. Chem., Aug 2003; 278: 30835 - 30842. , WB, , 3t3-L1 adipocytes

Glut1 Majumder PK (2004), mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways Nature Medicine10, 594 - 601 , WB,
glut1 Bindra RJ (2004), Down-Regulation of Rad51 and Decreased Homologous Recombination in Hypoxic Cancer Cells Mol. Cell. Biol., Oct 2004; 24: 8504 - 8518 , WB, , nonrl and hyp cancer cells

glut1 Hansen WJ eat al (2002), Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity Mol. Cell. Biol. 22: 1947-1960 , WB, ,glut1 Choeiri C (2002), Immunohistochemical localization and quantification of glucose transporters in the mouse brain Neuroscience 111, 19-34 , IHC, , IF, 4% PF, mouse brain

Glut1 Gunaratnam L (2003), HIF activates the TGF-/EGF-R growth stimulatory pathway in VHL-/- renal cell carcinoma cells, J. Biol. Chem., 278: 44966 - 44974 , WB, renal carcinoma cells

glut1 Greenberg CC (2003), Protein Targeting to Glycogen Overexpression Results in the Specific Enhancement of Glycogen Storage in 3T3-L1 Adipocytes J. Biol. Chem., Aug 2003; 278: 30835 - 30842. , WB, , 3t3-L1 adipocytes
Glut1 Kondo K (2002), Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein Cancer Cell 1, 237-246 , WB, far western/786-O renal cell carcinoma
Glut1 Schoenfeld, Alan (1998), A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor PNAS 95: 8817-8822 , WB, ,

glut1 Choeiri C (2004), Glucose transporter plasticity during memory processing Neuroscience, In Press , WB, mouse brain
Glut1 Mekhail K (2004), HIF activation by pH-dependent nucleolar sequestration of VHL Nature Cell Biology 6, 642 - 647 , WB,

glut1 Choeiri C (2004), Longitudinal evaluation of memory performance and peripheral neuropathy in the Ins2C96Y Akita mice Behavioural Brain Research, In Press , WB, mouse brain

Glut1 Lewis MD (2004), Role of the C-terminal -helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity Oncogene23, 2315 - 2323 , WB, Rcc4

glut1 Gnudi L (2003), GLUT-1 Overexpression: Link Between Hemodynamic and Metabolic Factors in Glomerular Injury? Hypertension, Jul 2003; 42: 19 - 24. , WB, , IHC, rat kidney

Glut1 CHENG, CM (2001), Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex FASEB J 2001 15: 907-915 , WB, , IHC, ,
Glut1 Gnudi L (2003), GLUT-1 Overexpression: Link Between Hemodynamic and Metabolic Factors in Glomerular
Injury? Hypertension. 42(1):19-24, July 2003 , WB, IHC, rat kidney

Glut1 Lewis MD (2003), Role of nuclear and cytoplasmic localization in the tumour-suppressor activity of the von Hippel-Lindau protein. Oncogene 22(26):3992-3997 , WB,

Glut-1 Brown RS (2002), Expression of hexokinase II and Glut-1 in untreated human breast cancer Nucl Med Biol. 29, 443-453 IHC, human, paraffin embedded sections

Glut-1 Qi H (2004), Molecular Cloning and Characterization of the von Hippel-Lindau-Like Protein Mol. Cancer Res., Jan 2004; 2: 43 - 52 , WB, , 3t3 and cat muscle

Glut-1 Baba Masaya (2003), Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor Oncogene22, 2728 - 2738 , WB, renal carcinoma cells
Glut-1 Barnes DM (2004), Effects of mercuric chloride on glucose transport in 3T3-L1 adipocytes Toxicology in Vitro, In Press , WB, mouse 3T3 adipocytes

Glut-1 Wright G (2003), Activation of the Prolyl Hydroxylase Oxygen-sensor Results in Induction of GLUT1, Heme Oxygenase-1, and Nitric-oxide Synthase Proteins and Confers Protection from Metabolic Inhibition to Cardiomyocytes J. Biol. Chem., May 2003; 278: 20235 - 20239,, WB, rat cardiomyocytes, Myocyte culture protein determination
Glut-1 (GT11) Stolze IP (2004), Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes J. Biol. Chem., Oct 2004; 279: 42719 - 42725 , WB, human cells

glut1/chicken Papoutsi, M (2001), Induction of the blood-brain barrier marker neurothelin/HT7 in endothelial cells by a variety of tumors in chick embryos Histochemistry and Cell Biology 113, 105-113 IHC, , chick embryo section

glut1-gt11 beasley NJP (2002), Hypoxia-inducible Factors HIF-1 and HIF-2 in Head and Neck Cancer Cancer Research 62, 2493-2497, May 1, 2002 , WB, HIH Mo from otehrs human head and neck tumor

Glut1h Charles A. Stuart, (2000), GLUT-3 expression in human skeletal muscle Am J Physiol Endocrinol Metab 2000 279: 855E-861E , WB, , IHC, , human skeletal muscle

glut1h Oliver RJ (2004), Prognostic value of facilitative glucose transporter Glut-1 in oral squamous cell carcinomas treated by surgical resection: results of EORTC Translational Research Fund studies European Journal of Cancer, Volume 40, Issue 4, March 2004, Pages 503-507 IHC, human tissues

Glut1h Cooper R (2003), Glucose transporter-1 (GLUT-1): a potential marker of prognosis in rectal carcinoma? British Journal of Cancer89, 870 - 876 IHC, human tumor/paraffin

glut1h garcia MDLA (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J. Neurochem., Aug 2003; 86: 709 - 724. , WB, ?

GLUT1h Grover-McKay, M (1999), Glucose transporter 3 (Glut3) protein is present in human myocardium BBA 1416, 145-154 , WB, , human heart

Glut-1h garcia MDL (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing Journal of Neurochemistry 86, Issue 3, Page 709-724 IHC, IF
Glut-1h Williams KJ (2002), A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis Oncogene 21, 282 - 290 IHC,

Glut-1h Al-Makdissy N (2003), Sphingomyelin/cholesterol ratio: an important determinant of glucose transport mediated by GLUT-1 in 3T3-L1 preadipocytes Cellular Signalling 15, 1019-1030 , WB, , NIH 3T# cells 3T3-L1 fibroblasts

Glut-1h Medina RA (2003), Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells Endocrinology, Oct 2003; 144: 4527 - 4535 , WB, , IHC, ZR-75 breast cance cells

Glut-1h Sowter HM (2003), Predominant Role of Hypoxia-Inducible Transcription Factor (Hif)-1 versus Hif-2 in Regulation of the Transcriptional Response to Hypoxia Cancer Res., Oct 2003; 63: 6130 - 6134. , WB, , breast renal cance cells
Glut-1h Lonergan, Kim M. (1998), Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2 Mol. Cell. Biol. 1998 18: 732-741 , WB, , renal carcinoma cells

Glut-1h venge P (2003), Mechanisms of basal and cytokine-induced uptake of glucose in normal human eosinophils: relation to apoptosis Respiratory Medicine 97, 1109-1119 Human Eosinophils Antibody blocks glucose uptake in live cells Glut1, 3, 4 more potent, 2% 5 minimla effect

Glut1-h Shikhman AR (2004), Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses Am J Physiol Endocrinol Metab, 286: 980 - 985 , WB, human chondrocyte

Glut-1human Rachel Airley, (2001), Glucose Transporter Glut-1 Expression Correlates with Tumor Hypoxia and Predicts Metastasis-free Survival in Advanced Carcinoma of the Cervix Clin. Cancer Res. 2001 7: 928-934 IHC, , 4%pf, cervix carcinoma

Glut-1human Burt BM (2001), Using Positron Emission Tomography with [ 18 F]FDG to Predict Tumor Behavior in Experimental Colorectal Cancer Neoplasia 3, 189-195 , WB,

Glut-1human Shikhman AR (2001), Cytokine Regulation of Facilitated Glucose Transport in Human Articular Chondrocytes J Immunol. 167, 7001-7008 , WB, Human Articular Chondrocytes

Glut-1m Karhausen J (2004), Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis J. Clin. Invest., Oct 2004; 114: 1098 - 1106 , WB,

Glut2 Hori Y (2002), Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells PNAS, Dec 2002; 99: 16105 - 16110 , WB, , IHC, , 4%PF, mouse pancreas

glut2 Lee S-H (2003), Cytoprotective Effects of Polyenoylphosphatidylcholine (PPC) on ß-cells During Diabetic Induction by Streptozotocin J. Histochem. Cytochem., Aug 2003; 51: 1005 - 1015 IHC, 4%PF rat pancreas

Glut2 Harrison, Kathleen A. (1999), Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice Nature Genetics 23, 71 - 75 IF

Glut2 "Brissova Marcela
Knobel3, David W. Piston3, Christopher V. E. Wright4 and Alvin C. Powers" (2002), "Reduction in Pancreatic Transcription Factor PDX-1 Impairs Glucose-stimulated
Insulin Secretion" J. Biol. Chem., Vol. 277, Issue 13, 11225-11232 , WB, , IHC, , 4%PF, mouse pancreas

Glut-2 Harrison, Kathleen A. (1999), Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice Nature Genetics Volume 23 Number 1 Page 71 - 75 (1999) , WB, TR3 death protein in most regions

Glut-2 Sumazaki R (2004), Conversion of biliary system to pancreatic tissue in Hes1-deficient mice Nature Genetics36, 83 - 87 IHC, mouse

glut-2 Rutjes, N (2002), Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model Kidney International 62 Issue 3 Page 832 IHC, mouse kidney

Glut-2 rat Rodriguez SM (2004), Influence of abomasal carbohydrates on small intestinal sodium-dependent glucose cotransporter activity and abundance in steers J Anim Sci, Oct 2004; 82: 3015 - 3023. , WB,
glut2h garcia MDLA (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J. Neurochem., Aug 2003; 86: 709 - 724. , WB, ?

Glut-2h venge P (2003), Mechanisms of basal and cytokine-induced uptake of glucose in normal human eosinophils: relation to apoptosis Respiratory Medicine 97, 1109-1119 Human Eosinophils Antibody blocks glucose uptake in live cells Glut1, 3, 4 more potent, 2% 5 minimla effect
Glut-2h Medina RA (2003), Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells Endocrinology, Oct 2003; 144: 4527 - 4535 , WB, , IHC, ZR-75 breast cance cells

Glut-2h garcia MDL (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing Journal of Neurochemistry 86, Issue 3, Page 709-724 IHC, IF

Glut3 Fattoretti, P (2001), Quantitative Immunohistochemistry of Glucose Transport Protein (Glut3) Expression in the Rat Hippocampus During Aging J. Histochem. Cytochem. 2001 49: 671-672 , WB, , IHC, , rat hippcocampus, frozen free floating section

glut3 Merriman-Smith BR (2003), Expression Patterns for Glucose Transporters GLUT1 and GLUT3 in the Normal Rat Lens and in Models of Diabetic Cataract Invest. Ophthalmol. Vis. Sci., Aug 2003; 44: 3458 - 3466 , WB, ,
Glut3 Fattoretti, P (2002), Decreased Expression of Glucose Transport Protein (Glut3) in Aging and Vitamin E Deficiency Ann. N.Y. Acad. Sci., Nov 2002; 973: 293 - 296 IHC, , rat brain frozen free floating sections

Glut3 Cheng CM (2001), Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex FASEB J 2001 15: 907-915 , WB, , IHC, ,

glut3/mouse brain Choeiri C (2002), Immunohistochemical localization and quantification of glucose transporters in the mouse brain Neuroscience 111, 19-34 IHC, , IF, 4% PF, mouse brain

glut3h garcia MDLA (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J. Neurochem., Aug 2003; 86: 709 - 724. , WB, ?

GLUT3h Grover-McKay, M (1999), Glucose transporter 3 (Glut3) protein is present in human myocardium BBA 1416, 145-154 , WB, , human heart

Glut3h Stuart CA (2000), GLUT-3 expression in human skeletal muscle Am J Physiol Endocrinol Metab 2000 279: 855E-861E , WB, , IHC, , human skeletal muscle

Glut-3h Medina RA (2003), Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells Endocrinology, Oct 2003; 144: 4527 - 4535 , WB, , IHC, ZR-75 breast cance cells

Glut-3h garcia MDL (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing Journal of Neurochemistry 86, Issue 3, Page 709-724 IHC, IF
Glut-3h venge P (2003), Mechanisms of basal and cytokine-induced uptake of glucose in normal human eosinophils: relation to apoptosis Respiratory Medicine 97, 1109-1119 Human Eosinophils Antibody blocks glucose uptake in live cells Glut1, 3, 4 more potent, 2% 5 minimla effect

Glut3-h Shikhman AR (2004), Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses Am J Physiol Endocrinol Metab, 286: 980 - 985 , WB, human chondrocyte

glut3-h gaster M (2002), Regenerating human muscle fibres express GLUT3 protein Eur J. Physiol. Sept 445, 105-114 IHC, human muscle/OCt compund

Glut-3human Shikhman AR (2001), Cytokine Regulation of Facilitated Glucose Transport in Human Articular Chondrocytes J Immunol. 167, 7001-7008 , WB, Human Articular Chondrocytes

GLUT4 Grover-McKay, M (1999), Glucose transporter 3 (Glut3) protein is present in human myocardium BBA 1416, 145-154 , WB, , human heart

Glut4 Cheng CM (2001), Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex FASEB J 2001 15: 907-915 , WB, , IHC, ,

Glut4 Rumsey SC (2000), Dehydroascorbic Acid Transport by GLUT4 in Xenopus Oocytes and Isolated Rat Adipocytes J. Biol. Chem 2000 275: 28246-28253 , WB, , adipocytes/oocytes

glut4 Tong, Haiyan (2000), Preconditioning Enhanced Glucose Uptake Is Mediated by p38 MAP Kinase Not by Phosphatidylinositol 3-Kinase J. Biol. Chem. 2000 275: 11981-11986 , WB, rat heart

Glut-4 Brennan CL (2004), GLUT4 but not GLUT1 expression decreases early in the development of feline obesity Domestic Animal Endocrinology, 26, 291-301 , WB, , 3t3 and cat muscle

Glut-4 Medina RA (2003), Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells Endocrinology, Oct 2003; 144: 4527 - 4535 , WB, , IHC, ZR-75 breast cance cells

glut4/mouse brain Choeiri C (2002), Immunohistochemical localization and quantification of glucose transporters in the mouse brain Neuroscience 111, 19-34 IHC, , IF, 4% PF, mouse brain

glut4h garcia MDLA (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J. Neurochem., Aug 2003; 86: 709 - 724. , WB, ?

Glut-4h garcia MDL (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing Journal of Neurochemistry 86, Issue 3, Page 709-724 IHC, IF
Glut-4h venge P (2003), Mechanisms of basal and cytokine-induced uptake of glucose in normal human eosinophils: relation to apoptosis Respiratory Medicine 97, 1109-1119 Human Eosinophils Antibody blocks glucose uptake in live cells Glut1, 3, 4 more potent, 2% 5 minimla effect

Glut4-h Otani K (2004), Calpain System Regulates Muscle Mass and Glucose Transporter GLUT4 Turnover J. Biol. Chem., May 2004; 279: 20915 - 20920. , WB, human muscle, tarsngegic

Glut-4m Fueger PT (2004), Control of exercise-stimulated muscle glucose uptake by GLUT4 is dependent on glucose phosphorylation capacity in the conscious mouse J. Biol. Chem., Sep 2004 , WB, mouse muscle ucp2, hxkii from cc

glut5h garcia MDLA (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J. Neurochem., Aug 2003; 86: 709 - 724. , WB, ?

Glut-5h venge P (2003), Mechanisms of basal and cytokine-induced uptake of glucose in normal human eosinophils: relation to apoptosis Respiratory Medicine 97, 1109-1119 Human Eosinophils Antibody blocks glucose uptake in live cells Glut1, 3, 4 more potent, 2% 5 minimla effect

Glut-5h garcia MDL (2003), Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing Journal of Neurochemistry 86, Issue 3, Page 709-724 IHC, IF
Glut-7 Li Q (2004), Cloning and Functional Characterization of the Human GLUT7 Isoform (SLC2A7) from the Small Intestine Am J Physiol Gastrointest Liver Physiol, Mar 2004; , , WB, , , IF rat intestine, lot#7440

Glut8-h Shikhman AR (2004), Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses Am J Physiol Endocrinol Metab, 286: 980 - 985 , , WB, , human chondrocyte

Glut-10-h Shikhman AR (2004), Distinct pathways regulate facilitated glucose transport in human articular chondrocytes during anabolic and catabolic responses Am J Physiol Endocrinol Metab, 286: 980 - 985 , WB, human chondrocyte

SGLT-1 Dieter M (2004), Regulation of Glucose Transporter SGLT1 by Ubiquitin Ligase Nedd4-2 and Kinases SGK1, SGK3, and PKB Obes. Res., May 2004; 12: 862 - 870 IHC, cell surface expression

SGLT-1 Lane RH (2002), IGF alters jejunal glucose transporter expression and serum glucose levels in immature rats Am J Physiol Regulatory Integrative Comp Physiol 283: R1450-R1460 IHC glut-2 from biogenesis rat midjejunum, EtOh fixed, paraffin sections'

SGLT-1 Rodriguez SM (2004), Influence of abomasal carbohydrates on small intestinal sodium-dependent glucose cotransporter activity and abundance in steers J Anim Sci, Oct 2004; 82: 3015 - 3023. , WB,
 

SGLT-2 Han HJ (2004), "Effects of TCDD and estradiol-17 on the proliferation and Na+/glucose cotransporter in renal proximal tubule cells †" ARTICLE
Toxicology in Vitro" Toxicology in Vitro in press , WB, rabbit tissues

SGLT-2 Bautista R (2004), Angiotensin II-dependent increased expression of Na+-glucose cotransporter in hypertension Am J Physiol Renal Physiol, Jan 2004; 286: 127 - 133 , WB, IHC, kidney

SGLT-2 Han HJ (2004), Signaling cascade of ANG II-induced inhibition of -MG uptake in renal proximal tubule cells Am J Physiol Renal Physiol, Apr 2004; 286: 634 - 642 , WB, rabbit PTC cells