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Fluorescent Calcium Indicators
and Related Products > Fluo-3
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Fluo-3 has its absorption maximum at
506 nm, thus making it excitable by the 488 argon-ion laser.
Unlike fura-2 and indo-1, neither the excitation nor the
emission maximum of the sensor shifts significantly before
and after Ca2+ binding. As a result, the ratioing
technique is not applicable to fluo-3. Fluo-3 is essentially
nonfluorescent without Ca2+ present, but the
fluorescence increases at least 40 times on Ca2+
binding. Also, because fluo-3 binds Ca2+ more
weakly (higher Kd) than do fura-2 and indo-1, it
is more useful for measuring high transient Ca2+
concentration during Ca2+ spikes. A major
application of fluo-3/AM is high throughput drug screening.
The quality of Biotium's fluo-3/AM is among the best (395%
by HPLC) while its price is the most competitive.
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Ref.: Minta, A., et al. J. Biol. Chem. 264, 8171(1989);
Kao, J.P.Y., et al. J. Biol. Chem. 264, 8179(1989).
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Product Name
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Price Per Unit *
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50010 |
Fluo-3, pentaammonium salt
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1mg
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50011 |
Fluo-3, pentapotassium salt
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1mg
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50012 |
Fluo-3, pentasodium salt
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1mg
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50013 |
Fluo-3, AM ester
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10x100ug
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50014 |
Fluo-3, AM ester
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1mg
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50015 |
Fluo-3, AM ester, 1mM in anhydrous DMSO
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1.0mL
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50016 |
Fluo-3, AM ester (special packaging)
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20x50ug
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Price is for US enduser only. International price may vary.
Please contact your local distributors for your price.
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All prices are quoted in US dollars,
and are subject to change without notice. Please contact us for
current prices. Any written confirmation of prices is valid for
30 days only. Please visit Order Gentaur's Product for further
details. |
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Many of our products are also
available in BULK QUANTITIES. Please inquire for BULK RATES
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