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Product Details: Anti-Receptor-Interacting
Serine/Threonine-Protein Kinase (RIP). IgG fraction (monoclonal)
Basic Information
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| Product ID: |
MR-1201-7 |
| Product Name: |
Anti-Receptor-Interacting
Serine/Threonine-Protein Kinase (RIP). IgG fraction
(monoclonal) |
| Unit: |
250µg |
| Price: |
465 € |
| Availability: |
Available |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Monoclonal Antibodies (Growth
Factors/Cytokines/Receptors) |
Product Details
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| Description: |
IgG fraction from mouse monoclonal
antibody (clone 9G11/G4) obtained by immunization of
mice with the recombinant N-terminal region of RIP (aa1
– aa430). The IgG fraction was purified using Protein
G-Sepharose.
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| Isotype: |
IgG-2b |
| Biological Activity: |
This antibody can be used for ELISA
assay (1:8,000 dilution) and Western Blot (1: 12,000
dilution). RIP is a serine/threonine kinase, component
of the active TNF receptor 1 signaling complex. It
contains three domains, including an N-terminal kinase
domain (aa1 – aa300), an intermediate domain, and a
C-terminal death domain. This protein is essential in
DNA damage-induced NF-?-B activation and in TNF-related
apoptosis-inducing ligand (TRAIL)-mediated apoptosis
signaling.
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| Formulation: |
Solution at 1.0 mg/mL in PBS |
| Storage Conditions: |
Store at -20oC |
| Stability: |
Stable for at least one year. Avoid
repeated freezing and thawing. |
| Temperature: |
-20°C |
| References: |
Meylan, E. et. al. (2004) Nat. Immunol.
5, 503 - 507.
Zhang, H-G. et. al. (2004) Oncogene 23, 2009 - 2015.
Hur, G.M. et. al. (2003) Genes & Dev. 17, 873 - 882.
Hsu, H. et. al. (1996) Immunity 4, 387 - 386. |
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