Anti-Recep.-Inter. Serine/Threonine-(RIP). IgG



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Product Details: Anti-Receptor-Interacting Serine/Threonine-Protein Kinase (RIP). IgG fraction (monoclonal)


Basic Information

Product ID:	MR-1201-4
Product Name:	Anti-Receptor-Interacting Serine/Threonine-Protein Kinase (RIP). IgG fraction (monoclonal)
Unit:	50µg
Price:	215 €
Availability:	Available
Category:	Growth Factors, Cytokines, Receptors and their Antibodies
Subcategory:	Monoclonal Antibodies (Growth Factors/Cytokines/Receptors)


Product Details

Description:	IgG fraction from mouse monoclonal antibody (clone 9G11/G4) obtained by immunization of mice with the recombinant N-terminal region of RIP (aa1 - aa430). The IgG fraction was purified using Protein G-Sepharose.
Isotype:	IgG2b
Biological Activity:	This antibody can be used for ELISA assay (1:8,000 dilution) and Western Blot (1: 12,000 dilution). RIP is a serine/threonine kinase, component of the active TNF receptor 1 signaling complex. It contains three domains, including an N-terminal kinase domain (aa1 – aa300), an intermediate domain, and a C-terminal death domain. This protein is essential in DNA damage-induced NF-?-B activation and in TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis signaling.
Formulation:	Solution at 1.0 mg/mL in PBS
Storage Conditions:	Store at -20oC
Stability:	Stable for at least one year. Avoid repeated freezing and thawing.
Temperature:	-20°C
References:	Meylan, E. et. al. (2004) Nat. Immunol. 5, 503 - 507. Zhang, H-G. et. al. (2004) Oncogene 23, 2009 - 2015. Hur, G.M. et. al. (2003) Genes & Dev. 17, 873 - 882. Hsu, H. et. al. (1996) Immunity 4, 387 - 386.