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Product Details: Anti-Interleukin-4 Receptor Alpha chain
(Il-4R) extracellular domain (CD124). IgG fraction (monoclonal)
Basic Information
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| Product ID: |
MR-441-7 |
| Product Name: |
Anti-Interleukin-4 Receptor Alpha chain
(Il-4R) extracellular domain (CD124). IgG fraction
(monoclonal) |
| Unit: |
250µg |
| Price: |
465 € |
| Availability: |
Available |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Monoclonal Antibodies (Growth
Factors/Cytokines/Receptors) |
Product Details
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| Description: |
IgG fraction from mouse monoclonal
antibody (clone 6B1/E7) obtained by immunization of mice
with the extra-cellular domain of interleukin 4 receptor
alpha chain (38 kDa). The IgG fraction was purified
using Protein G-Sepharose.
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| Isotype: |
IgG1 |
| Biological Activity: |
This antibody can be used for ELISA
assay (1:2,000 dilution). The IL-4R alpha chain binds
both IL-4 and IL-13 and activates many common signal
transduction pathways. The extra-cellular domain, also
called CD124, inhibits IL-4-mediated cell proliferation
and IL-5 up-regulation by T-cells. The IL-4/IL-13
responses are involved in the regulation of the
differentiation of CD4+ T cells and class switching to
IgG1 and IgE.
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| Formulation: |
Solution at 0.95 mg/mL in PBS |
| Storage Conditions: |
Store at -20oC |
| Stability: |
Stable for at least one year. Avoid
repeated freezing and thawing. |
| Temperature: |
-20°C |
| References: |
Nelms, K. et. al. (1999) Annu. Rev.
Immunol. 17, 701 - 738 |
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