Anti-hTNF R.A.F. 2 (TRAF 2). IgG



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Product Details: Anti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal)


Basic Information

Product ID:	MR-951-7
Product Name:	Anti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal)
Unit:	250µg
Price:	465 €
Availability:	Available
Category:	Growth Factors, Cytokines, Receptors and their Antibodies
Subcategory:	Monoclonal Antibodies (Growth Factors/Cytokines/Receptors)


Product Details

Description:	IgG fraction from mouse monoclonal antibody (clone 2I10/I5) obtained by immunization of mice with human TRAF2 (50 kDa). The IgG fraction was purified using Protein G-Sepharose.
Isotype:	IgG1
Biological Activity:	This antibody can be used for ELISA assay (1:2,000 dilution). TRAF2 is a signal transducer protein that associates with the cytoplasmic domain of TNF receptor to different signaling pathways. It regulates two distinct kinase cascades which lead to NF-?B and JUNK activation. It is also involved in anti-apoptotic signaling, perinatal survival and IL-15 signaling.
Formulation:	Solution at 1.0 mg/mL in PBS.
Storage Conditions:	Store at -20oC
Stability:	Stable for at least one year. Avoid repeated freezing and thawing.
Temperature:	-20°C
References:	Chung, Y.J. et. al. (2002) J. Cell. Sci. 115, 679 - 688. Bradley, J.R. & Pober, J. (2001) Oncogene 20, 6482 - 6491. Wajant, H. et. al. (2001) Cell. Signal. 13, 389 - 400.