DESCRIPTION
Urea is primarily produced in the liver and secreted by the kidneys. Urea is
the major end product of protein catabolism in animals. It is the primary
vehicle for removal of toxic ammonia from the body. Urea determination is
very useful for the medical clinician to assess kidney function of patients.
In general, increased urea levels are associated with nephritis, renal
ischemia, urinary tract obstruction, and certain extrarenal diseases, e.g.,
congestive heart failure, liver diseases and diabetes. Decreased levels
indicate acute hepatic insufficiency or may results from over-vigorous
parenteral fluid therapy.
Simple, direct and automation-ready procedures for measuring urea
concentration in biological samples are very popular in clinical studies.
BioAssay Systems' urea assay kit is designed to measure urea directly in
biological samples without any pretreatment. The improved Jung method
utilizes a chromogenic reagent that forms a colored complex specifically
with urea. The intensity of the color, measured at 520nm, is directly
proportional to the urea concentration in the sample. The optimized
formulation substantially reduces interference by substances in the raw
samples.
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